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Download Current Research and Clinical Management of Melanoma by Howard K. Koh, Thomas H. Sinks (auth.), Larry Nathanson PDF

By Howard K. Koh, Thomas H. Sinks (auth.), Larry Nathanson (eds.)

In our environmentally wide awake society, stories of a rise within the possibility of constructing numerous cancers - together with cancer, lymphoma and lung melanoma - have excited nice controversy. of those tumors, cancer has tested the main surprising bring up, producing a substantial physique of analysis. The justification for this quantity is located within the want for an updated evaluate of this learn. The publication represents a complete evaluate of either present study and medical administration of cancer, prepared in this kind of manner as to be maximally hassle-free to either the fundamental scientst and the clinician drawn to this interesting disease.

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J Clin Oncol 2:994-1000. 35. Swerdlow AJ, English J, MacKie RM, et al. 1986. Benign melanocytic naevi as a risk factor for malignant melanoma. Br Med J 292:1555-1559. 36. , Tucker MA, et a1. 1985. High risk of malignant melanoma in melanoma-prone families with dysplastic nevi. Ann Intern Med 102:458-465. 37. Kopf A W, Lindsay AC, Rogers GS. 1985. Relationship of nevocytic nevi to sun exposure in dysplastic nevus syndrome. J Am Acad Dermatol 12:656-662. 38. Rampen FHJ, Fleuren BAM, de Boo THM, et al.

6). Finally, efforts in both Europe and the United States to look for changes in histopathologic criteria or to adjust for indices of ascertainment have not found evidence for a methodologic artifact sufficient to account for a substantial portion of the observed increases [69,70]. Increases such as those observed over the past 50 years cannot continue indefinately. It may be argued that the lifestyles prevaling in Australasia, Europe, and North America with respect to sun exposure are already maximally melanomagenic, given the existing levels of environmental ultraviolet radiation, and have been so for many years.

174. Holly EA, Kelly JW, Shpall SN, et al. 1987. Number of melanocytic nevi as a major risk factor for malignant melanoma. J Am Acad Dermatol 17:459-468. 175. Osterlind AM, Tucker M, Stone B, et al. 1988. The Danish case-control study of cutaneous malignant melanoma. II. Importance of UV-light exposure. Int J Cancer 42:319-324. 176. Sober AJ. 1987. Solar exposure in the etiology of cutaneous melanoma. Photodermatol 4:23-31. 2. Epidemiology of melanoma Martin A. Weinstock 1. 1. Race and ethnicity One of the most striking features of melanoma epidemiology is the dramatic differences in patterns observed among racial groups.

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