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GERSCHENFELD, H. M. & TAUC, L. (1961). , 189, 924. GLAIZNER, B. (1967). In: Neurobiology of Invertebrates, ed. , p. 267. New York: Plenum Press. KEHOE, J. S. & ASCHER, P. (1970). , 225, 820. KERKUT, G. A. (1967). In: Invertebrate Nervous Systems, ed. Wiersma, C. A. , p. 5. Chicago University Press. 44 Acetylcholine, dopamine and a specified snail neurone KERKUT, G. A. (1969). In: Handbook of Neurochemistry, Vol. 2, ed. , p. 539. Plenum Press. KERKUT, G. D. , LoKER, J. & WALKER, R. J. (1973). Comp.

Root, W. S. & Hofmann, F. , p. 179. London: Academic Press. ELLIS, S. & BECKETT, S. B. (1963). J. Pharmac. exp. , 142, 318. GREEN, R. , DALE, M. M. & HAYLETT, D. G. (1972). Experientia, 28, 1073. HAYLETT, D. G. & JENKINSON, D. H. (1968). Br. J. , 34, 694P. HAYLETT, D. G. & JENKINSON, D. H. (1969). , 224, 80. HAYLETT, D. G. & JENKINSON, D. H. (1972a). J. , 225, 721. HAYLETT, D. G. & JENKINSON, D. H. (1972b). J. , 225, 751. HORNBROOK, K. R. (1970). , 29, 1381. JENKINSON, D. H. & MoRTON, I. K. M. (1965).

2 shows the result of such an experiment. Fig. 2b shows the normal preparation in 4 mM K control solution. ___. J 11 mV '----' 1 mV DA ACh 200 nA 60 nA FIG. 2. The effect of changing the external potassium concentration on the ACh- and dopamine-induced hyperpolarization. The cell membrane potential was initially at -41 mY, and brought to this value after each change of solution by passing a current through the electrode. Normal control solution contained 4 mM potassium (b). Decreasing the external potassium concentration to zero (a) increased the hyperpolarization whilst increasing the external potassium concentration to 8 mM (c) decreased the hyperpolarization.

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